NMN supplements improved gait speed and lowered ALT liver enzyme levels in middle-aged and older adults in a meta-analysis of 9 RCTs.
Meta-analysis of 9 randomised controlled trials with 412 middle-aged and older participants; NMN improved gait speed and lowered ALT.
Resveratrol supplements improved flow-mediated dilation, a marker of blood-vessel function, in a meta-analysis of 17 randomised trials.
Meta-analysis of 17 RCTs (21 arms); resveratrol raised flow-mediated dilation by 1.43% and lowered the adhesion molecule ICAM-1.
NMN at 300-900 mg a day raised blood NAD levels and walking distance versus placebo in healthy middle-aged adults over 60 days.
Double-blind RCT, 80 healthy middle-aged adults taking placebo or 300, 600 or 900 mg NMN daily for 60 days; NAD levels and six-minute walk distance rose versus placebo, highest at 600 and 900 mg, and NMN was well tolerated.