Berries of the chaste tree.
Why it’s used: Traditionally used to support women’s monthly cycle.
Chaste tree (Vitex agnus-castus) is a Mediterranean shrub with spikes of lilac flowers and small, peppery berries. The berries, often sold as chasteberry or agnus castus, are the part used. Its long history stretches back to ancient Greece and Rome, and it was traditionally used for gynaecological complaints and hormone-related skin conditions.
In supplements you will see it listed as agnus castus, chasteberry or Vitex agnus-castus fruit extract, usually in capsules or tablets, sometimes standardised to a specific extract. It appears on its own and in blends for women's health, where it often sits alongside herbs such as dong quai, black cohosh or sage.
Chaste tree is traditionally used to support women's monthly cycle. Researchers have studied chasteberry extracts in several trials looking at premenstrual symptoms such as breast tenderness, and some findings have been encouraging, though most of the studies were of low to moderate quality. Smaller studies have also looked at menopausal symptoms, and more research is needed before conclusions can be drawn.
3 findings behind this ingredient. Hover a card for the detail and the source.
Meta-analysis of three double-blind, placebo-controlled trials (520 women) of the extracts Ze 440 and BNO 1095. Women taking chaste tree were significantly more likely to respond than those on placebo.
Systematic review of 17 randomised trials, 14 in the meta-analysis, lasting at least two cycles. The pooled effect versus placebo was large (Hedges g -1.21), with high heterogeneity and risk of bias.
Review of 25 studies (17 randomised); a meta-analysis of six trials (718 women) found a moderate effect favouring chaste tree (SMD 0.67). Doses of 20 to 40 mg a day for 3 months were typical, with mild side effects.
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Yes. Agnus castus, chasteberry, chaste tree and Vitex all refer to the same plant, Vitex agnus-castus. Supplements use the dried berries, usually as an extract in a capsule or tablet.
Agnus castus is traditionally taken over several monthly cycles rather than for quick effects. Research studies have generally run for around three months. If you have troubling symptoms, it is worth speaking to your GP so they can be properly assessed.
It is generally well tolerated in the short term. Reported side effects are usually mild and include nausea, stomach ache, diarrhoea, headache and itching. Stop taking it and seek advice if you notice anything that concerns you.
Videos from doctors, research scientists and registered dietitians, for general education. They are independent of Nutra Formulations, do not refer to our products and are not medical advice for you.
Chasteberry (Vitex) for PMS and Irregular Periods: Easing Mood Swings and Hormone Imbalance Naturally
Dr Patricia Mills, MD, holistic and hormone medicine · Dr. Patricia Mills MD | Holistic Health & Hormones on YouTube
Information only, not medical advice. If you take medication, are pregnant or breastfeeding, speak to your GP or pharmacist first.
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