3 findings behind this formula. Hover a card for the detail and the source.
In adults with mild to moderate depression, St John's wort produced more treatment responders than placebo and matched antidepressants.
Systematic review and meta-analysis of 35 RCTs (6,993 adults with major depressive disorder). St John's wort gave more responders than placebo (18 RCTs, 2,922 people), was as effective as antidepressants, and had fewer adverse events.
A single 200 mg dose of L-theanine improved attention, measured by reaction time, in healthy adults versus placebo.
Systematic review and meta-analysis of 31 placebo-controlled RCTs (1,168 people). A 200 mg dose taken 30-60 minutes before testing significantly improved choice reaction time, indicating better attention.
In adults with stress-related fatigue, Rhodiola rosea extract reduced burnout scores and improved concentration compared with placebo over 28 days.
Double-blind RCT, 60 adults aged 20-55 with fatigue syndrome taking 576 mg/day Rhodiola rosea extract (SHR-5) or placebo for 28 days. Rhodiola beat placebo on burnout scores and attention measures and lowered the cortisol response to waking.